Bookcover of The effectiveness of CRISPR-Cas9
Booktitle:

The effectiveness of CRISPR-Cas9

Treatment of Duchenne muscular dystrophy

Our Knowledge Publishing (2021-01-11 )

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ISBN-13:

978-620-3-20765-1

ISBN-10:
6203207659
EAN:
9786203207651
Book language:
English
Blurb/Shorttext:
Duchenne Muscular Dystrophy (DMD) is a lethal pathology that strikes the skeletal and cardiac muscle system, gradually leading to death due to cardiopulmonary failure. This genetic deformity occurs from mutations in the sequence of genes that encode the dystrophin in such a way as to damage the solidity of the sarcolema, which can cause destruction of muscle fibers. DMD is an X-linked recessive disease generally present in males with an incidence rate of 1 in 5000 live births. In the mid 1980s, the CRISPR method(Clustered Regularly Interspaced Short Palindromic Repeats) was created and later associated with the Cas9 protein with the proposal of offering more simplicity and accuracy in terms of editing DNA sequences. This book is developed with the main focus on the analysis of the effectiveness of the CRISPR/Cas9 system in the treatment of Duchenne Muscular Dystrophy (ICD 10 G71.0) compared to traditional therapy.
Publishing house:
Our Knowledge Publishing
Website:
https://sciencia-scripts.com
By (author) :
Leonardo Assis, Danielli Carolina Souza, José Antonio Souza
Number of pages:
80
Published on:
2021-01-11
Stock:
Available
Category:
Medicine
Price:
4263.24 руб
Keywords:
Cas9, CRISPR, Muscular dystrophy, Duchenne, Gene Therapy

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