Bookcover of Spi-1 (PU.1) 5' UTR Regulatory Element
Booktitle:

Spi-1 (PU.1) 5' UTR Regulatory Element

Betascript Publishing (2011-08-18 )

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ISBN-13:

978-613-7-65284-8

ISBN-10:
613765284X
EAN:
9786137652848
Book language:
English
Blurb/Shorttext:
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. The Spi-1 (PU.1) 5' UTR regulatory element is an RNA element found in the 5' UTR of Spi-1 mRNA which is able to inhibit the translation Spi-1 transcripts by 8-fold. Spi-1 regulates myeloid gene expression during haemopoietic development. Mutations in this regulatory region of the 5' UTR can lead to overexpression of Spi-1 which has been linked to development of leukaemia. A messenger ribonucleic acid (mRNA) molecule codes for a protein through translation. The mRNA also contains regions that are not translated: in eukaryotes these include the 5' untranslated region, 3' untranslated region, 5' cap and poly-A tail.
Publishing house:
Betascript Publishing
Website:
http://www.betascript-publishing.com/
Edited by:
Lambert M. Surhone, Mariam T. Tennoe, Susan F. Henssonow
Number of pages:
80
Published on:
2011-08-18
Stock:
Available
Category:
Microbiology
Price:
3333.72 руб
Keywords:
RNA Element

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