Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. In enzymology, a sphingosine N-acyltransferase (EC 2.3.1.24) is an enzyme that catalyzes the chemical reaction acyl-CoA + sphingosine rightleftharpoons CoA + N-acylsphingosine. Thus, the two substrates of this enzyme are acyl-CoA and sphingosine, whereas its two products are CoA and N-acylsphingosine. This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:sphingosine N-acyltransferase. Other names in common use include ceramide synthetase, and sphingosine acyltransferase. This enzyme participates in sphingolipid metabolism.