Bookcover of MMP & TIMP levels in Drug Induced Gingival Overgrowth in Rats
Booktitle:

MMP & TIMP levels in Drug Induced Gingival Overgrowth in Rats

Gingival MMP and TIMP Levels in Cyclosporine and Tacrolimus Induced Gingival Overgrowth in rats

LAP LAMBERT Academic Publishing (2012-04-10 )

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ISBN-13:

978-3-8484-9895-6

ISBN-10:
3848498952
EAN:
9783848498956
Book language:
English
Blurb/Shorttext:
With the need followed by success of organ transplantation, use of immunosuppressive drugs has become a necessity. Cyclosporine, one of the commonly used immunosuppressive drug has an undesirable side effect of gingival overgrowth. Whereas gingival overgrowth is an infrequent side effect with Tacrolimus, a potent immunosuppressive drug, when compared to Cyclosporine. Eventhough several hypothesis have been put forward, the exact mechanism underlying this untoward effect is not fully understood. This book attempts to review all the pathogenic mechanism in general and also discuss an experimental study done on wister rats comparing collagen content, MMP1, MMP2 and TIMP1 in Cyclosporine and Tacrolimus induced gingival overgrowth. This book will provide insight to researchers about the influence of drugs on connective tissue metabolism.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
http://www.lap-publishing.com/
By (author) :
Sheeja S Varghese, Ambiti Rajesh
Number of pages:
100
Published on:
2012-04-10
Stock:
Available
Category:
Dentistry
Price:
4679.94 руб
Keywords:
Collagen, tacrolimus, MMP, TIMP, Cylosporine, Gingival overgrowth

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